Endocrine Abstracts

Introduction: Dual oxidase 2(DUOX2) is NADPH oxidase complex at the apical membrane of the thyroid follicular cells which produce H2O2 required for thyroid hormone synthesis. DUOX2 gene mutation is a well known cause of congenital hypothyroidism (CH), the phenotype depends on the type of mutation and environmental factors.Case: We present a case of 29 years old female delivered a male baby with large neonatal goitre and severe CH who was started immediat...

Stress related cardiomyopathy or Takotsubo LV dysfunction has been described in phaeochromocytoma related cardiomyopathy.16 y female, admitted in A&E on 23 June 2013 with severe epigastric pain, vomiting and dyspnoea. History of episodes of palpitations and exertional syncopal attacks for 2 years, for which she had been investigated. Her symptoms were attributed to panic attacks. There was no known family history of Endocrinopathy. On admission, BP w...